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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4849a22e1e000bb7fbe54cec30e101801a22e3f1b7024b908343cc0561866314' 
  AND token = 'edSTP19F+piwwrKRQ3gzeIrMwVkEdabSHhIXlKrxs7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}