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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16362a011d4a36593988c5a1f8eccfa4018b4509d8e828f4549d927c934425a6' 
  AND token = 'NkwxHN/0sp3ciYOHdx9ujISl29BiIjpIyYTsWhi4Mb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}