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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3438649be3e6f90f8fe816822e3534ae311600c778c110f4a45ecf7454c96532' 
  AND token = '0T8KZ97AWcyE5YJuhgos9DeGxKqITIVVowsa2fNbOyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}