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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59da92310ffd04cb8d109036b0aa1f67ca00194a1dab8dddb7840a340afbd207' 
  AND token = 'vcfGwa49C1wr3s2Ge1h6RW+6zOGmm6qlFHDmyP2Rkco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}