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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2057e69c00b923fa2b49abfbf805b6c41295e8576822da6236b4099c2bbef4d' 
  AND token = 'W4wKJECusMmuTuAtVSv0MaIkn9S13HgBbviB9L+yCW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}