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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f255c40229ee9699b3eaef428bab736acf9ca44628771491da3618f088f857b' 
  AND token = 'Xu3qH0+AFd+2/ox5ZGqSAjAc9enNxbPBA7011BWUIEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}