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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73db0e2f650c224e1a95daa64f9d697c84b08e9997befb006f8332151614f8a8' 
  AND token = 'E7qyLj7LzFYQ6z3kreP9T5qHJvXQfkvk8Tn0YN6TdSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}