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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cc11f7641b36b40046940a7bf6acd235331087ef51fa91e6b9f03c1c170d19a' 
  AND token = 'yjl2GC7oAf4L/rvwzMTTNeEDNZL50n+s5Xl6hljAxjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}