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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea652ab9d8a23acf19f21b30957c9b926e8a7247e7b651111828de110de0e3d1' 
  AND token = 'NFttElpdq/ydU2EJZcVvnalKvRFXuXS6JOG9s1XF/Z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}