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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d7910dc669f4a7503e9bd465cd2d2acf5470b0133596bda8dc7e4a78e4b0a4b' 
  AND token = 'uP+Hm0383BxeabG0OvSUZ9Rbjb+hmVLrEHt8n+3+5KA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}