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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46d6231a835778dec87f9eec22c4f49f33c4c4ca140f58c6c0003501469c7a21' 
  AND token = '8TVaRo6+hLp3OHJbi5lbPPQNJ2PYJVxiTLnJztJfZeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}