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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73ceb6c7472afb130b10ef0e9c227f9a25696c21902a02059da3c70b4b17c21e' 
  AND token = 'TrfHX11+AfobvYLipeq69peR0pqXkbyg78qA8lNlO24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}