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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '354607b6410a965290dadcccfb7c2d59516bd642b6325ec8bb16c66f3b65d1ea' 
  AND token = '3tOnmPOmmWIddMfFBXt7gK5RwHAXiZ4U/1/TGkKnz2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}