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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8b9849e2045117eedd29536fc07261c32670b3eadad19df9a846dabab41f061' 
  AND token = '0AMnQsnznBsMCDtaKKdPhtsAsE4gNIwIBZ0Txj9MPjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}