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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a53baa3d8c30d89854f5f62db1b08ba00b10829018f5ab29bba4ebf5d06aaa1a' 
  AND token = 'OsKST5iKO3VnttndHSfrH18ZDPCI19uFEN40BwaMW5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}