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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cff4e9dffd8c1ad1649c70eca70ca8ca2e3750e8ed6dbda9624d81dd0c5ef8c' 
  AND token = 'XSQrs3OsbGOiVZdgK4KWFL6SQbFSQ8OtGRCUkzd1dPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}