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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d720650bda3d8d097d7ddcf7a15a0175b5a72198ddd626a223638513531362e' 
  AND token = 'oxpJIQkYI7HQRTP7DOW21xG+qKpJlVv4Et9PjFKn9LE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}