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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f678e9efa3718f0be8fe7e5ff117e14ec4a2f63e31e73558e87de84c2f13cbb' 
  AND token = 'WS+XgxDN+db/5n+Jsjmv2aVvfZCp2tQaYwlAF2pG3cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}