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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b5c1ddb2582c3aae1bae835c0850ac5ff727dc7e663e971befc4f11e9eed5a0' 
  AND token = 'Iy+oxc62gxR15v+tEAUMKTWL7eDKQGuClDqy79xeVAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}