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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b8ab4c4f844a47863ff884cbefbdda5fe412c07576e04fac51b795b836d0dac' 
  AND token = '0Y3yRJUv7Y7P+0UPMTKkA+ud9TJRbNtwESkMm/IC/R4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}