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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1b3af1a0160a77e9dc1b9555b491c6d3b946cf904eafa77045e326d6edba393' 
  AND token = 'WvPiHa9b4Oby5+w5P35E62PbrJrYAedkxumWajJSevc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}