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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f31e44cf570ef6864e3e81a610179edd075bbdf4a32e37b2a9422c1f97b130' 
  AND token = 'v1v7IOAGapwnbUyM63swDH/Nu/viYCihkTMs93XR2oU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}