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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18be6adb2b0dc7dbe20e751359898faff24ecdc9a7073bb469aeb288eaf2aac5' 
  AND token = 'Ofc+QetCamuWeq9Sg33HE7nagbsJTs5qzV4MNAgowEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}