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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ef4a32c7a84cd6bf6c07101314247a18e21206ecb6964d11e27d3c0ba002c89' 
  AND token = 'txzW6Qaf0bCUNMpbHK5TYzxLq3n0rEoFKXm2tfTjssI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}