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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d0ed714e7ddc02064acca97a3c8b04c71eed13acba23fbd4f4a99729b467349' 
  AND token = '+gdM3eItoLaMsS7yjJSyEq802p8j/NB74QZyW1SmYdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}