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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '734e8724f658da069cda978339e4f17241667e2c985f1b14b2d2e58838e757c8' 
  AND token = '/0D72L9YU1MrtRF7rQi8cwi573AXiwbUJr9cUEd79cI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}