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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44bf64db3e3333d3d85e9d209073a2e44b0f7a3224366cad65875d2ecd53f849' 
  AND token = 'cOdd3SVI9rE13rLbkjZFKrEz13VvxE8vlz46SCB/lG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}