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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53069872e66613e69500a42f87208596a3da3b82c17f5630856e4434f2b08136' 
  AND token = 'WCunONUMvaDro4+k806r33Mk4K6fH6wYZ4UVYBX0Jk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}