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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a46e222a833f7961572e258cbcb6f0209a707eca2983d6c464c5108cdb5e315' 
  AND token = '5tM2E0sP6LEGWNieDs62hHhpsPp7rmm9XauL1mh7GWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}