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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '857ed80494adc7d63d5fe171b37bda69208fc9cdf90e363a3fc20660e6e93caf' 
  AND token = 'GKktMe4HRBKtndGKJt9yyGhGv0wytb5uhvsd0QBN/Ew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}