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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4e2d82749e1053082404cc263c4e2596188883643ab73af8180fa35ce8cf43a' 
  AND token = '5WdK0lNYL3dfWJZngEbQX44cz6bgxAI1QUyDxSyBxcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}