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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '580a558b4dd66bfc5f95837eada0fd8a16d0223907a4db00f3ead42535776a74' 
  AND token = 'Bs9iAmr0pdpdEwi4+xtJIBUeGfFM6AASy/5GBFgaEo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}