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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41edbc3732128d0ca3898c8fc1dad105f4b7f160db7ebc404024f1cda215e78b' 
  AND token = 'Vl1s1Gl4vhhJ20LZkR5FPwJLTCR1pU6BNAd+Wu+hypw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}