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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46cd64663178a625f75f49d63dbd515d554421f1644373680c81650431c47cd8' 
  AND token = 'bc5QvF6hEOCWRTw0AtUeIw00XeZEYG1WgcbLe4h0RvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}