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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e7547e4bbfb0eaf527eba2f5757f2f6e07a30bed66023f4d503707cf8404fa3' 
  AND token = 'Mtnjgkm+oNKd24Y8EPTHyKRV06tbJX4Gp2gUXSdbR2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}