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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95e75bb7ba07f2ffa05e8da1e3097019f2b0fb9afb77d88224f3ddd20bbc3710' 
  AND token = 's7D8S9ZcCBhxl+TpzEMCn7tcdM9W/IFCnx/ybiXX9Eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}