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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3fc02a5184c2fe8abc3fbc019ff116dc4676b76b17ab6456270f03c79331450' 
  AND token = 'HUarb2Un8w6Eokfsc236isIdTg4imNeuNZZbjem/k30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}