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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ec6784c313b2b13be69cb9700b5b8517bd6ab0683bf60e0c650b929e25410e7' 
  AND token = 'QrEpwSL3A6GRJKI6ko/SR1FWVbD0ueTebqRVus7XcQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}