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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76b8c57ce48ea279f6607d65d5cc0608c72ef276ed08d764f6514c9120d2447a' 
  AND token = 'VVLVNBcLQdgu4/2JYYs6VK9anVOmqMAVSxNHs22Rh3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}