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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29727734c186b8e99208cd75ec8944b2bc02e7d305d02691758fbdd9ca2758e8' 
  AND token = 'rY1XMiUCXeeKCvzgZ+8GJ7rUns5me5IOkld+cPCY9dM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}