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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb9b303a16b054d38a07d7d0fb31542915030170af523f450091b8a4b0778be4' 
  AND token = 'hG96nde20tZwrYyHerSHHWAqbd6WmOMfi6igAy+Li4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}