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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e82175aa00c1ddf4966a61d60ea792fc9fa9b057508c41e9310be2f7e4cbc392' 
  AND token = 'IZdXH3zK4sNEvfgKhH2R9Xm+FMFD0SOtqELjRsr4uW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}