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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd42d43cd20a49df7b654ef3a774a40fb1b5aa5525560f1859fa662cbb401b100' 
  AND token = '/NmUrYj/bvfr/e1TyLe7uFq6ZITNKhX6EnS7DhdZfDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}