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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f414e6252ba6bb9167236328f7eb87036850402fb644061d1afc0b2acde65fc4' 
  AND token = 'nzo3HiSbcdl92QdMfuxI0Pjwu7cMH0CM8Uf9I2qflc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}