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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3246791fac70d2438fa6f677a02e78fd4082d17f0514db5e51222c110f012aa' 
  AND token = '/zInn09GFRmzSWWF5A9NKlQ9/kLUByA4SnibdcJelVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}