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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7335e0fe28e46b8b423d6ab38bdcd0deac773bee5e56eb788e77fabaa7de53a8' 
  AND token = 'OgvNi0WAT45kaz7TwQG3gQrCelCkTJ0FKMYt/g6Ja5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}