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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b15127ff75cc64fa9c8776b0920ec165c1d7108d8121bc87b5ab91742b0a045b' 
  AND token = '4/XR5eIrUVHmEFJd2huGxQlWNdsb+wNaRpjBGjcSskg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}