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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f45e9eb5276a55a7f2a97fcb8527ad3b76ae4acb2fd420d701335818522af9b' 
  AND token = '9iVAYQuo4PKVtrgS52ZMs2J0qHbixXrM5nbHLAQ1XxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}