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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61ec67d308642d6b4ec9b68d8fff44b1cb054e2f1eda1bc8f15269e17fec5227' 
  AND token = 'c6ODAVKX+frsv1xXRTOeOkpyNorobiLtmC0yBo1VXTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}