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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2487d5261ebd79f155ce79b0468740e75bb3ea07b3f72c68b4b8b15d9f66e205' 
  AND token = 'beLuuCk9qJTu8MR/di0cTyezoJPoBF6I7+dYpe/4Qg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}